LEQEMBI PATIENT
AND CARE PARTNER
STORIES

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NINA’S LEQEMBI® STORY:
Living with mild cognitive impairment (MCI) and still finding positivity

People shown were compensated for their time, and information is accurate as of
August 2026.

SELECTED SAFETY INFORMATION

LEQEMBI can cause serious side effects, including amyloid-related
imaging abnormalities or “ARIA.” ARIA can cause serious symptoms or be
fatal. Symptoms can look like stroke symptoms, and include headache,
confusion, dizziness, vision changes, nausea, difficulty walking, seizures,
difficulty speaking, or muscle weakness. Additionally, serious allergic reactions,
such as swelling of the face, lips, mouth, or tongue, hives, or difficulty
breathing, as well as infusion-related reactions and injection-related reactions,
can happen during LEQEMBI treatment.

This is not a complete list of all potential side effects. Please see full
Important Safety Information at the end of this video.

Nina
VO: I was too young to give up on myself, so I decided to go to the LEQEMBI infusions.

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NINA
LEQEMBI PATIENT SINCE 2023

Megan
VO: … My mom is who I wanna be when I grow up.

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MEGAN
Nina’s daughter

Nina
VO: I love to sing, I sing in church, I sing in the car, and I like to be with my friends.

Nina
VO: My book club, so that’s a fortunate thing, that I have a lot of good people.

Megan
VO: And just recently with the diagnosis, I know that it’s harder for her.

Nina
VO: I was diagnosed with early stages of Alzheimer’s, mild cognitive impairment

Greg
VO: Her doctor kind of laid out that LEQEMBI was an option.

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GREG
Nina’s husband

Greg
VO: We did take some time to understand and learn about the possible side effects.

Megan
VO: She was like, just so positive.

Nina
VO: I enjoy going to the LEQEMBI infusions.

[On-screen text]
Your experience may be different. Talk to your healthcare provider to learn more.

Nina
VO: People there are very nice to me. And it’s been well worth it.

Nina
VO: I just feel very fortunate to live where I live, live around my family.

Megan
VO: They always say that you always come back to your momma.

Nina
VO: Part of my joyfulness is…

Nina
VO: … knowing that a lot of people love me.

Megan
VO: She’s watching me do what she’s done all these years, and now I’m…

Megan
VO: … she’s teaching me how to be a mom, so, it’s pretty cool.

Nina
VO: I think it’s very important to enjoy the life that you have as best you can.

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YOU STILL CAN BE WITH LEQEMBI

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WHAT IS LEQEMBI?
LEQEMBI is a prescription medicine used to treat people with early Alzheimer’s disease,
which includes mild cognitive impairment (MCI) or mild dementia stage of disease.

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about LEQEMBI?
LEQEMBI can cause serious side effects, including:

• ARIA (amyloid-related imaging abnormalities). ARIA is a side effect that does not usually
  cause any symptoms, but serious symptoms can occur. ARIA can be fatal.
• ARIA commonly shows up as temporary swelling in areas of the brain that usually
  goes away over time
• Small spots of bleeding in or on the surface of the brain can occur
• Less often, larger areas of bleeding in the brain can occur
• Most people with ARIA don’t have any symptoms. However, some people may
  notice:
  • headache
  • confusion
  • dizziness
  • vision changes
  • nausea
  • difficulty walking
  • seizures
  • difficulty speaking
  • muscle weakness
• Some people have a gene called ApoE4 that may increase the risk of ARIA. Talk to
  your healthcare provider about testing to see if you have this gene
• You may be at a higher risk of developing bleeding in the brain if you take
  medicines to reduce blood clots from forming (antithrombotic medicines) while
  receiving LEQEMBI. Talk to your healthcare provider to see if any of the
  medicines you’re taking increase this risk
• Your healthcare provider will check for ARIA with MRI (magnetic resonance imaging)
  scans before you start LEQEMBI and during treatment
• You should carry information that says you are receiving LEQEMBI, which can
  cause ARIA, and that ARIA can look like stroke symptoms

Call your healthcare provider or go to the nearest hospital emergency room right away
if you have any of the symptoms mentioned previously.

Serious allergic reactions:
Do not receive LEQEMBI if you have serious allergic reactions to LEQEMBI,
LEQEMBI IQLIK, or any of the ingredients.

Tell your healthcare provider and get medical help right away if you notice any symptoms
during or after treatment with LEQEMBI, including: swelling of the face, lips, mouth, or
tongue; itchy bumps on the skin, also known as hives; difficulty breathing

Infusion-related reactions:
Infusion-related reactions are a common side effect that can occur during or after completion
with LEQEMBI injection into a vein (intravenously), which can be serious. Tell your healthcare
provider right away if you notice any of these symptoms: fever; flu-like symptoms (chills, body
aches, feeling shaky, joint pain); nausea and/or vomiting; dizziness or lightheadedness; fast or
slow heart rate, or feeling like your chest is pounding; difficulty breathing or shortness of breath;
changes in blood pressure

If you have an infusion-related reaction, your healthcare provider may give you
medicines before your next infusion to lower the chance of having a reaction

Injection-related reactions:
Injection-related reactions may occur with LEQEMBI injection under the skin (subcutaneous
injection with LEQEMBI IQLIK). Tell your healthcare provider if you notice any of these
symptoms during or after an injection: redness, swelling, heat, pain, itching, rash, bump,
bruising, and blood collection under the skin at the injection site; headache, chills, fatigue, or
fever may also be observed after an injection

The most common side effects of LEQEMBI include infusion-related reactions with
LEQEMBI injected into a vein, ARIA, and headache.

These are not all the possible side effects of LEQEMBI. Call your doctor for more
information and medical advice about side effects. You may report side effects to the FDA
at www.fda.gov/medwatch or call 1-800-FDA-1088.

Before receiving LEQEMBI, tell your healthcare provider about:
All your medical conditions, including if you are pregnant, breastfeeding, or plan to
become pregnant or breastfeed. It is not known if LEQEMBI could harm your unborn or
breastfeeding baby

All the medicines you take, including prescription and over-the-counter medicines,
vitamins, and herbal supplements. Especially tell your healthcare provider if you take
medicines to reduce blood clots from forming (antithrombotic medicines, including
aspirin)

LEQEMBI (lecanemab-irmb) is available as:
Intravenous infusion: 100 mg/mL
Subcutaneous injection: 200 mg/mL

Please see Medication Guide with Instructions for Use and full Prescribing
Information, including Boxed WARNING, on LEQEMBI.com.

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© 2026 Eisai Inc. and Biogen.
LEQE-US5592 August 2026
All trademarks are the property of their respective owners.
LEQEMBI® and LEQEMBI IQLIK® are registered trademarks of Eisai R&D
Management Co., Ltd.